Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5979
Gene Symbol: RET
RET 		0.700 CausalMutation disease CLINVAR Phase II trial of sorafenib in advanced thyroid cancer. 18541894 2008
Entrez Id: 5979
Gene Symbol: RET
RET 		0.700 CausalMutation disease CLINVAR The effects of four different tyrosine kinase inhibitors on medullary and papillary thyroid cancer cells. 21470995 2011
Entrez Id: 5979
Gene Symbol: RET
RET 		0.700 CausalMutation disease CLINVAR Phase II clinical trial of sorafenib in metastatic medullary thyroid cancer. 20368568 2010
Entrez Id: 5979
Gene Symbol: RET
RET 		0.700 CausalMutation disease CLINVAR AZD1480 blocks growth and tumorigenesis of RET- activated thyroid cancer cell lines. 23056499 2012
Entrez Id: 5979
Gene Symbol: RET
RET 		0.700 CausalMutation disease CLINVAR Phase II study of daily sunitinib in FDG-PET-positive, iodine-refractory differentiated thyroid cancer and metastatic medullary carcinoma of the thyroid with functional imaging correlation. 20847059 2010
Entrez Id: 5979
Gene Symbol: RET
RET 		0.700 CausalMutation disease CLINVAR Vandetanib in patients with locally advanced or metastatic medullary thyroid cancer: a randomized, double-blind phase III trial. 22025146 2012
Entrez Id: 5979
Gene Symbol: RET
RET 		0.700 CausalMutation disease CLINVAR Targeted therapies for thyroid tumors. 21455200 2011
Entrez Id: 673
Gene Symbol: BRAF
BRAF 		0.700 CausalMutation disease CGI
Entrez Id: 5979
Gene Symbol: RET
RET 		0.700 CausalMutation disease CLINVAR Molecular biology of the MEN2 gene. 9681850 1998
Entrez Id: 5979
Gene Symbol: RET
RET 		0.700 CausalMutation disease CLINVAR Phase II trial of sorafenib in metastatic thyroid cancer. 19255327 2009
Entrez Id: 5979
Gene Symbol: RET
RET 		0.700 CausalMutation disease CGI
Entrez Id: 5979
Gene Symbol: RET
RET 		0.700 CausalMutation disease CLINVAR Vandetanib for the treatment of patients with locally advanced or metastatic hereditary medullary thyroid cancer. 20065189 2010
Entrez Id: 3845
Gene Symbol: KRAS
KRAS 		0.680 CausalMutation disease CLINVAR Selumetinib-enhanced radioiodine uptake in advanced thyroid cancer. 23406027 2013
Entrez Id: 3845
Gene Symbol: KRAS
KRAS 		0.680 CausalMutation disease CLINVAR Beneficial effects of sorafenib on tumor progression, but not on radioiodine uptake, in patients with differentiated thyroid carcinoma. 19773371 2009
Entrez Id: 3845
Gene Symbol: KRAS
KRAS 		0.680 CausalMutation disease CLINVAR Phase II trial of sorafenib in metastatic thyroid cancer. 19255327 2009
Entrez Id: 3845
Gene Symbol: KRAS
KRAS 		0.680 CausalMutation disease CGI
Entrez Id: 3845
Gene Symbol: KRAS
KRAS 		0.680 CausalMutation disease CLINVAR Hyperactive Ras in developmental disorders and cancer. 17384584 2007
Entrez Id: 4893
Gene Symbol: NRAS
NRAS 		0.480 CausalMutation disease CGI
Entrez Id: 3265
Gene Symbol: HRAS
HRAS 		0.460 CausalMutation disease CLINVAR Phase II trial of sorafenib in metastatic thyroid cancer. 19255327 2009
Entrez Id: 3265
Gene Symbol: HRAS
HRAS 		0.460 CausalMutation disease CLINVAR Selumetinib-enhanced radioiodine uptake in advanced thyroid cancer. 23406027 2013
Entrez Id: 3265
Gene Symbol: HRAS
HRAS 		0.460 CausalMutation disease CLINVAR Hyperactive Ras in developmental disorders and cancer. 17384584 2007
Entrez Id: 3265
Gene Symbol: HRAS
HRAS 		0.460 CausalMutation disease CLINVAR Prospective enterprise-level molecular genotyping of a cohort of cancer patients. 25157968 2014
Entrez Id: 3265
Gene Symbol: HRAS
HRAS 		0.460 CausalMutation disease CLINVAR Beneficial effects of sorafenib on tumor progression, but not on radioiodine uptake, in patients with differentiated thyroid carcinoma. 19773371 2009
Entrez Id: 5573
Gene Symbol: PRKAR1A
PRKAR1A 		0.350 CausalMutation disease CGI
Entrez Id: 5979
Gene Symbol: RET
RET 		0.700 AlteredExpression disease LHGDN RET expression in papillary thyroid cancer from patients irradiated in childhood for benign conditions. 12161537 2002